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Dibutyltin dichloride

ULingshi udla ngokubizwa ngokuba Ubuhle kwaye ibhaliswe njenge-686-48-2 iyaziwa kwaye iqeshwe kwiinkalo ezininzi amashumi eminyaka. Yinto enetyhefu kwizinto eziphilayo zasemanzini kwaye yenza amanzi amdaka kwaye ibe neempembelelo kwiinkqubo zehomoni ze-mollusks, i-crustaceans, intlanzi ekhokelela ekwakhiweni kwamalungu akhubazekileyo ngenjongo yokuvelisa kunye neenkqubo ze-metabolic kunye ne-immune system. [ s]. Ngaphaya koko, i-DBTDC iyakwazi ukonakalisa zonke iinkalo zokukhula kwezinto eziphilayo zasemanzini kunye nokuziphatha okumangalisayo kunye nokuthomalalisa I-DBTDC nayo yonzakalisa indawo eyingqongileyo kuba ingcolisa umhlaba namanzi, nto leyo engabazuzisi ubomi baselwandle kuphela. Nje ukuba zikhutshelwe kwindawo ezingqongileyo, ii-DBTDCs ziyafunxwa zizidalwa eziphilayo eziquka abantu kwaye zinokuqokelelwa kwimixokelelwane yokutya eneziphumo ezibi zexesha elide. Uyakuqaphela ukuba i-DBTDC inetyhefu kangakanani emva kokuphonononga iipropati zayo zekhemikhali. I-DBTDC ine-molecular formula ye-C8H18Cl2Sn kwaye i-organotin compound. Lulwelo olungenambala ukuya kumthubi oluluthuthu olunyibilikayo kwisithathu sezona zinyibilikisi zisetyenziswa kakhulu: iacetone, methanol, kunye nebenzene. Ezi datha zibonisa ukuba i-DBTDC inetyhefu ephezulu kunye nefuthe elinamandla lokucinezela i-acetylcholinesterase. Ukunyanzeliswa kwe-acetylcholinesterase kubangela ukuqokelelwa kwe-acetylcholine kunye nokufa kwayo kwe-nerve. I-DBTDC iphinda iphazamise iinkqubo zehomoni. Umthetho womhlaba namanzi Uphando lwe-DBTDC lungqongqo kungcoliseko lokusingqongileyo. Kwezi zifundo, iikhemisti zisebenzisa iindlela ezahlukeneyo, ukusukela kuhlalutyo ukuya kuhlalutyo lwe-bioassay ukuya kumsebenzi wendalo.

Inkqubo yetyhefu yeDibutyltin Dichloride

Uya kuqonda ukuba yityhefu kangakanani uLingshi i-organotin reagents ngokwenene emva kokuthatha ujongo kwiimpawu zekhemikhali. Ifomula yemolekyuli yi-C8H18Cl2Sn. I-DBTDC yeyodidi lweekhompawundi ze-organotin Lulwelo olungenambala ukuya kokukhanyayo olutyheli olunokunyibilika kwizinyibiliki ezithathu ezisetyenziswa kakhulu ezizezi: iacetone, methanol kunye nebenzene.

Ezi ziphumo zibonisa ubutyhefu obuphezulu kunye nefuthe elinamandla lokuthintela i-acetylcholinesterase yi-DBTDC kulawulo lwenkqubo ye-nervous. Ukuvinjelwa kwe-acetylcholinesterase kubangela ukuqokelelwa kwe-acetylcholine, ngoko ke i-nerve-death ekugqibeleni ikhokelela ekufeni. I-DBTDC iphinda ibangele ihomoni ekhokelela ekuzaleni kakubi kunye nemetabolism

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